The purpose of this study was to explore a biopsychosocial profile for experiencing sexual harassment and abuse in sports.A qualitative approach was used; data were collected from semi-structured in-depth interviews covering seven cases of sexual harassment and abuse in sports in the Netherlands.The interview transcripts were analysed and aligned w

Abstract Background Increased serum level of parathyroid hormone (PTH) was found in metastatic prostate cancers.Calcimimetic R-568 was reported to reduce PTH expression, to suppress cell proliferation and to Baking Essentials induce apoptosis in parathyroid cells.In this study, we investigated the effect of R-568 on cellular survival of prostate ca

Sponges (phylum Porifera) had been considered as an enigmatic phylum, prior to the analysis of their genetic repertoire/tool kit.Already with the isolation of the first adhesion molecule, galectin, it became clear that the sequences of sponge cell surface receptors and of molecules forming the intracellular signal transduction pathways triggered by

Abstract Receptor tyrosine kinases (RTKs) play a crucial role in the regulation of intracellular signal transduction, underscoring their significance as targets for drug therapy.Despite the widespread clinical use Spanners of kinase inhibitors, the increasing occurrence of off-target effects and drug resistance makes it urgent to explore alternativ

Abstract Background Ocean acidification (OA), a change in ocean chemistry due to the absorption of atmospheric CO2 into surface oceans, challenges biogenic calcification in many marine organisms.Ocean acidification is expected to rapidly progress in polar seas, with regions of the Southern Ocean expected to experience severe OA within decades.Biolo